Vitamin D Testing - The Gold Standard for Controls

Back in 2003, the decision to begin manufacturing Vitamin D Controls in human serum was easy - published research studies began to link Vitamin D deficiency to several different health problems. The decision to use a 100% REAL human serum matrix was not easy. At the time, the variability in reference methods (EIA, RIA, HPLC, LC-MS) and the controversy surrounding which method was best for measuring 25-Hydroxyvitamin D (25-OH D), the accepted marker for Vitamin D nutritional status, made using 100% REAL human serum a gamble.

It would have been much easier to use stripped serum, "human based" serum, or human serum fortified with animal serum. However, we could not, in good conscience, sacrifice the quality of our products with these inferior matrix choices. Ultimately, it could affect a patient's quality of life. Though we knew that using a 100% REAL human serum matrix presented serious challenges to manufacturing Vitamin D Controls, that's how our journey began.

First, we needed to accurately measure the endogenous levels of 25-OH D to establish a baseline response for each human serum pool used during manufacturing. Second, we needed to accurately spike-in additional amounts of 25-OH D to achieve clinically relevant reference values, which is similar to hitting a moving target. Third, the reference values had to be verified by HPLC and "standardized" so that our control could be utilized with any analytical technique.

Two years of research and development turned into the products you see on this website, and UTAK is now proud to be recognized as the undeniable world leader in serum Vitamin D Controls.

Currently, the assays for measuring 25-OH D in serum are still not standardized and the controversy rages on about which reference method is the "gold standard".

However, there is no controversy surrounding UTAK Vitamin D Controls - our proprietary manufacturing process coupled with an unwavering commitment to quality has enabled us to set the standard for all Vitamin D Controls. Our quality control improves your quality of life.

That's the 100% REAL STORY.